3D Printing
Core Capabilities:
3D printing
Fabrication of medical-grade parts
Fabrication of biocompatible parts
Contact: Adam Verga
Advanced Bioinformatics
Core Capabilities:
Bioinformatics
Computational genomics
Transcriptomics analysis
Molecular typing
Machine learning
Biostatistical analysis
Contacts:
King Jordan
Andrew Conley
Biomechanics
Core Capabilities:
Rheology, viscosity measurements
Torsion test, thin film tension test accessories
Uniaxial Compression, tensile, torsion testing
Cyclic fatigue testing
Flexural testing
Contact: Laxmi Krishnan
Biomolecular Analysis
Core Capabilities:
Laser capture microdissection
Gel, blot, and tissue imaging
PCR analysis
Freeze drying
Fluorescence absorbance and luminescence analysis
Contact: Robert Hughley
Biopolymer Characterization
Core Capabilities:
HPLC
FPLC
Circular dichroism/fluorescence
Size exclusion chromatography
Multimode DLS
Ultracentrifugation
Multimode DSF
Stopped flow
High throughput absorbance/fluorescence /chemiluminescence
ITC
Stop flow kinetics analysis
Analytical ultracentrifugation
Protein stability analysis
High-performance and ultracentrifugation
Contact: Robert Hughley
Cellular Analysis and Cytometry
Core Capabilities:
Spectral Flow Cytometry (up to 40 color Fluorescence Detection System)
Conventional Flow Cytometry (up to 18 color Fluorescence Detection Systems)
Fluorescence Activated Cell Sorting (2-way, 4-way, and Plate with Index Sorting)
Imaging Flow Cytometry
Mass Cytometry and Tissue Imaging Mass Cytometry
Particle Sizing and Counting from 0.2um - 1600um
Nanoparticle Counting and Characterization
Contact: Core Lab Manager
Genome Analysis
Core Capabilities:
qRT-PCR & RT-PCR
Nucleofection
Single cell isoation (large sample number)
Single cell isolation (small sample number)
Digital drop PCR
Contact: Naima Djedder
High Throughput DNA Sequencing
Core Capabilities:
Rapid runs with and without reagents
High output
TruSEq DNA
Nextera DNA
Nextera XT
TruSEq RNA sequencing
Nextera rapid capture
Nextera library quantification
TruSEq quantification
NOVA SEQ
Oligonucleotide synthesis
Contact: Shweta Biliya
Histology
Core Capabilities:
Paraffin and Resin Automatic & Manual Tissue Processing
Cryogenic
Paraffin & Resin Embedding
Paraffin, Resin and Cryo-Microtomy
Diamond Saw Sectioning
Hematoxylin & Eosin Stain
Special Stains and Immunohistochemistry
Antigen Retrieval
Exakt Grinding System Slides
Histology Consulting & Training
Grossing
Plant Histology
Sample Decalcification
Tissue Fixation
Coverslipping
Protocol Optimization
Contact: Histology
Magnetic Resonance Imaging (MRI)
Core Capabilities:
Small Animal MRI
Engineering Applications of MRI
Magnetic Resonance Spectroscopy
flow-MRI
MRI technology
Contact: Johannes Leisen
Microcomputed Tomography
Core Capabilities:
Specimen scans (soft tissues, bones, thin stents)
Resolution: 1.2 um to 100 um
Sample size: (3 mm dia x 1 cm tall) to (10 cm dia x 10 cm tall)
Fluoroscopy (2D x-ray time lapse scans)
Live animal scans (in vivo CT)
Resolution: 7 um – 36 um
Fluoroscopy (2D x-ray time lapse scans)
CT Image reconstruction and analysis support
Contact: Laxmi Krishnan
Molecular Evolution
Core Capabilities:
Genome Sequencing
Library preparation/construction
Plasmid sequencing
Sanger sequencing
Next Gen sequencing
RNASeq
Automated sample Handling Automated
Phage Display
Cloning
Fragment Analysis
Yeast Surface Display
Automated Colony picking
Library Screening
Gel extraction
Oligonucleotide synthesis
Bacterial Surface Display
Custom ELISA
Error Prone PCR
Bioanalyzer; DNA; RNA; Protein, Electroporation
Custom Selection Systems Design
ScFvs
Qiacube DNA; RNA; Protein Purification
Colony Picking
Custom Sequencing Libraries
Competent Bacterial Cells
Contact: Anton Bryksin
Optical Microscopy
Core Capabilities:
Laser scanning confocal
Spinning disk confocal
Multi-photon excitation- inverted and upright
Lightsheet
Widefield and Slide/plate scanner
TIRF microscopy
Super resolution SIM
Super resolution- dSTORM and PALM
Swept field Confocal
LaserCapture Microdissection
Contacts:
Sandy Hsieh
Danielle Scheff
Systems Mass Spectrometry - Metabolomics
Core Capabilities:
Non-targeted polar and/or non-polar metabolomic assays
Targeted assays
Exact mass measurement
Mass spectrometry imaging
Sample preparation, data collection, data processing, data analysis, annotation, and interpretation
Contact: David Gaul
Systems Mass Spectrometry - Proteomics
Core Capabilities:
Discovery and targeted proteomics
Protein identification and quantification
Protein-Protein interaction studies
Posttranslational modification analysis
Intact protein analysis, protein complex characterization
ScFvs
Qiacube DNA; RNA; Protein Purification
Colony Picking
Custom Sequencing Libraries
Competent Bacterial Cells
Contact: Rakesh Singh