Biomechanics

  • Anton Parr MCR302 Rheometer 
  • TA Instruments ElectroForce 3200 uniaxial interchangeable Axial Extended Stroke (high displacement) or Axial/Torsion configuration 
  • TA Instruments ElectroForce 3100 uniaxial material testing system (small displacement/load) 
  • MTS MiniBionix 858 uniaxial servo-hydraulic material testing system (axial/ torsion)

Biomolecular Analysis

  • Beckman Coulter Analytical HPLC 
  • LiCor Biosciences Odyssey CLX infrared imager  
  • Agilent Bioanalyzer DNA, RNA and Protein Analysis 
  • Labconco Centivap Concentrator/Cold Trap speed vac system (2) 
  • Labconco FreeZone 6 Freeze Drying System (2)  
  • Revity Tri-Carb LSC 4910TR scintillation counter 
  • Amaxa Nucleofector cell electroporator 
  • Perkin Elmer IVIS Spectrum CT in vivo imaging system  
  • Applied Biosystems Step One Plus sequence detector  
  • Beckman Allegra R15 benchtop centrifuge 
  • Optima Max XP benchtop ultra centrifuge 
  • Packard Cobra II auto-gamma counter,  
  • Beckman Coulter XPN 100 ultracentrifuge  
  • Avanti J1-30I high speed centrifuge 
  • Fast Prep Tissue Homogenizer 
  • Biotek Synergy H4 multi-mode plate reader (2)  
  • GE FLA 9500 Imager 
  • GE AI 600 RGB Imager 

Cellular Analysis and Cytometry

  • Amnis Imagestream X imaging flow cytometer 
  • Fluidigm Helios Platform Mass cytometer and Hyperion imaging mass cytometer  
  • BD S8 cell sorter 
  • BD Melody Cell sorter w/ VBR lasers 
  • Beckman Coulter CytoFLEX S flow cytometer w/ plate loader  
  • Cytek Aurora full spectrum cytometer w/ automated sample loader 
  • IZON Exoid Tunable Resistive Pulse Sensing (TRPS) instrument  
  • Beckman Coulter Multisizer 4e cell counter 
  • NucleCounter NC-202  
  • LiCor DLx Gel Imager 

High Throughput DNA Sequencing

  • Illumina NovaSeq 6000 High throughput DNA sequencing system 
  • Element Bioscience AVITI sequencer 

Histology

  • Accu-Scope EXC-350 Brightfield Microscope w/ 4K HDMI Camera 
  • Buehler Ecomet 3 Grinder 
  • Epredia Autostainer 360 for IHC, IF, and MultiPlex Staining 
  • Epredia ClearVue Coverslipper 
  • Epredia Cryostar NX-70 Cryostat w/ Vacuum 
  • Epredia PT Module for Antigen Retrieval 
  • EXAKT Grinding System 
  • General Data Paraffin Dispenser PRO 
  • General Data TECII 2120 Tissue Embedding System 
  • Intelsint RTPH-360 Enclosed Tissue Processor 
  • Leica Autostainer XL 
  • Leica CM3050S Cryostat 
  • Leica VT1000 S Vibratome 
  • Lunaphore LabSat Multiplex IHC 
  • Metkon Miracut 152 Precision Saw 
  • Thermo Scientific Cryostar NX-70 Cryostat 
  • VWR 1400E Vacuum Oven 
  • Waldorf (Germany) HM355S Microm Rotary Microtome (2) 
  • Zeiss 100M Fluorescence Microscope w/ Camera 

Magnetic Resonance Imaging (MRI)

  • Bruker PharmaScan 7T MRI Scanner 

  • SAII animal monitoring and gating system 

  • Volume and surface coils in various sizes and configurations from Bruker, Doty Scientific and M2M imaging 

Microcomputed Tomography

  • MicroCT40 Small specimen scanner (Scanco) 
  • MicroCT50 Small specimen scanner (Scanco) 
  • VivaCT40 In vivo specimen scanner (Scanco) 
  • Inveon In vivo specimen scanner (Siemens) 
  • IVIS Spectrum CT Live animal scanner (Revvity) 
  • RS-2000 small animal X-ray irradiator (RadSource) 

Optical Microscopy

  • Zeiss LSM900 Confocal w/Airyscan or AI-sample finder 
  • Zeiss LSM980 Multiphoton 
  • Zeiss LSM780 Elyra ps1 
  • Zeiss AxioObserver Z1 Widefield 
  • Biotek Cytation 7 w/Biospa/Biostack Robotic Imaging System 
  • Zeiss Laser Capture Microdissection 
  • MD ImageXpress Pico Imager system 
  • Zeiss LSM700/710 Confocal 

Systems Mass Spectrometry - Metabolomics

  • Vanquish Horizon LC / ThermoFisher Scientific Q Exactive HF MS  
  • Vanquish Horizon LC / ThermoFisher Scientific Orbitrap ID-X MS  
  • Vanquish Horizon LC / ThermoFisher Scientific Exploris 240 MS (2) 
  • Bruker Amazon Speed Ion Trap with ETD 
  • Bruker rapiFlex MALDI TOF 
  • ThermoFisher Scientific GC / ISQ 7610 MS  
  • ThermoFisher Scientific Dionex Ultimate 3000 RSLC 

Image Data Analysis Services

  • ORS Dragonfly (academic license) 

  • Materialise Mimics suite (academic license) 

  • Imaris suite (academic license) 

  • Other open-source tools: 

    • 3Dslicer 

    • Micro Dicom Viewer 

    • HistoCAT 

    • Cell Profiler 

    • ImageJ (Fiji) 

Krone Engineered Biosystems Building (EBB)

Cellular Analysis and Cytometry

  • BD FACSAria Fusion  
  • BD LSR Fortessa 
  • BD Melody Cell sorter (B/YG/R lasers) 
  • Isoplexsis IsoLight single cell proteomics analyzer 
  • Axion Biosystems Maestro Pro multi-well microelectrode array (MEA) and impedance system  
  • Cytek Aurora full spectrum cytometer w/ automated sample loader 
  • Beckman Coulter CytoFLEX S flow cytometer w/ plate loader 

Genome Analysis

  • Bio Rad QX200 ddPCR 
  • Qiagen QIAcuity digital PCR system 
  • 10X Genomics Chromium X System  
  • Biopolymer Characterization Core 
  • BioTek Synergy H4 Microplate Readers  
  • AP Chirascan™-plus CD Spectrometer 
  • Olis RSM1000 Stopped-Flow Spectrophotometer 
  • Shimadzu NEXERA with RI, Fluorescence and PDA detector  
  • Wyatt DynaPro NanoStar Dynamic Light Scattering 
  • GE AKTAPure 25M with refrigerator 
  • GE Ultrospec 2100 pro UV-Vis Spectrometer  
  • OmniSEC REVEAL 
  • OnmiSEC 
  • Malvern Zeta-sizer (zeta potential measurement)  
  • Beckman XPN ultracentrifuge 
  • Beckman Avanti centrifuge 
  • Wyatt Dynapro plate reader (DLS with HTS capacity) 
  • Prometheus nanoDSF (native differential scanning fluorimeter)  
  • Nanotemper technologies  
  • MicroCal VP-DSC 2M (Differential scanning calorimeter) 
  • MicroCal iTC200 (Isothermal calorimetry) 
  • Beckman Optima AUC + Schlieren optics (analytical ultracentrifugation) 

Molecular Evolution (Research)

  • ABI Step One Plus real time PCR system 
  • Electrophoresis equipment 
  • NuAire NU 475-500 PCR workstation 
  • Illumina MiSeq system 
  • Illumina iSEQ system  
  • Illumina NextSeq 500 
  • Illumina MiniSeq 
  • Oxford Nanopore MinION 
  • Grenova Tip Washer  
  • BIOSETT ASM 2000 DNA oligo synthesizer  
  • Qiagen Qiacube Connect nucleic acid extraction system 
  • Tissuelyser II sample disruptor 
  • Agilent Tapestation 4200 
  • Agilent Bioanalyzer 2100 
  • Sage Science Blue Pippin automated gel extraction system 
  • Covaris R230 focused ultrasonicator 
  • ThermoFisher Scientific SeqStudio Sanger sequencing system 
  • ThermoFisher Scientific SeqStudio Flex Sanger sequencing system 
  • Beckman Coulter Echo 525 acoustic liquid handling system  
  • Crocodile ELISA Robot  
  • Qpix 2XT Colony picker 
  • Andrew Alliance Liquid Handling System  
  • DXS Automated ELISA System  
  • Tapestri Single cell Multi-omics system 

Molecular Evolution (CLIA Lab)

  • BSC LYSIS Hood 
  • Traceable® Ultra-Low Temperature WIFI Data Logger with TraceableLIVE® Cloud Service Pipette Communication Module 
  • Integra Assist PLUS liquid handling system  
  • BMG Labtech CLARIOstar Plus plate reader  
  • California Air Compressor 
  • KingFisher Flex nucleic acid extraction system 
  • Thermo Scientific Quantstudio 5 real time PCR system 
  • Thermo Scientific Quantstudio 6 Flex real time PCR system 
  • SPT Labtech XL-100 automated liquid handling system 
  • Formulatrix Mantis liquid handling system 
  • Omni bead ruptors 

Optical Microscopy

  • Zeiss Lattice SIM 3 
  • Nikon Spinning Disk Confocal 
  • PE Spinning Disk Confocal 
  • Bruker Opterra Sweptfield Confocal 
  • Bruker Investigator Upright Multiphton and FLIM 
  • Zeiss Lightsheet Z1 
  • Bruker Vutara Super-Resolution 

Systems Mass Spectrometry - Proteomics

  • Dionex UltiMate 3000 RSLCnano UHPLC system / ThermoFisher Scientific QE Plus MS (2) 
  • TimsTOF HT with nanoelute2 LCMS system 
  • Waters Acquity I Class LC 
  • Beckman PF-2D Chromatography system 
  • VanquishNeo LC/ThermoFisher Scientific Exploris480 
  • Thermo Scientifc Nanodrop Lite Plus 
  • Cole-Palmer Freezer/Mill Compact Cryogenic Grinder 

Molecular Science and Engineering Building (MoSE)

Systems Mass Spectrometry

  • Bruker Solarix 12T FTICR 

Whitaker Building

3D Printing Core

  • Stratasys J750 Digital Anatomy PolyJet 3D Printer