A fluorescent microscopy image showing a large cluster of cells with bright purple centers and green outlines against a dark background.

Stem Cell

Through partnerships with Emory and UCLA, Georgia Tech researchers have access to specialized stem cell services, including CRISPR genome engineering, gene editing, iPSC reprogramming, cell characterization and differentiation, gene tagging and knockout, and clonal screening. These capabilities support disease modeling, functional genomics, regenerative medicine, and other advanced stem cell research applications.

Emory Stem Cell and Organoids Core

Patient-derived induced pluripotent stem cells (iPSCs) have multiple applications in modeling diseases, drug discovery and screening, toxicological studies and cell therapy, paving the way towards personalized medicine. Emory Stem Cell and Organoids Core provides important support to investigators in Emory University, the state of Georgia and beyond. Our services include:

  • Somatic cells reprogramming to iPSCs
  • Development of organoid models (brain, lung) from patient-derived 
  • iPSC differentiation into 2D models
  • Genome editing in human iPSCs

UCLA Stem Cell Core

Integration Free iPSC Reprogramming  

  • Human fibroblasts 
  • Peripheral blood mononuclear cells (PBMCs)  

Pluripotent Stem Cell Characterization & Differentiation 

  • Whole Genome Sequencing–Based Genomic Stability Assay
  • Immunocytochemistry for pluripotency markers (OCT4, SSEA4)
  • Trilineage differentiation assay 
  • Mycoplasma testing   

CRISPR Genome Engineering 

  • Gene knockout 
  • Safe harbor locus engineering (e.g. AAVS1 site) 
  • Inducible Knockout/CRISPR activation/CRISPR inhibition 
  • Vector/gRNA design & cloning 

Location

Atlanta, Georgia (Emory University)

University of California, Los Angeles (UCLA) 

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